Therapeutic effect of imiquimod on dextran sulfate sodium-induced ulcerative colitis in mice
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Therapeutic effect of imiquimod on dextran sulfate sodium-induced ulcerative colitis in mice
BACKGROUND Imiquimod is a Toll-like receptor-7 agonist that regulates immunity and can be used as an immune adjuvant. Ulcerative colitis has a close correlation with immune disorder. AIM To investigate the therapeutic effect of imiquimod on dextran sulfate sodium (DSS)-induced colitis and explore the underlying mechanisms. METHODS C57BL/6J C57 mice received 3% DSS for 7 days to induce ulcer...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2017
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0186138